Set in Quebec at the turn of the 19th to 20th century, the story of Agnes White, a lonely orphaned girl fascinated by the "wrong" things--microscopes, dissections, and anatomy instead of more ladylike interests--who rises to the status of one of the world's most celebrated pioneering women doctors. Not only does she break through patriarchal academic barriers; she masters the science of the human heart, becoming a scholar of international fame, all in a place and time inimical to intelligent women. Inspired by the career of Maude Abbott, one of Canada's first female physicians.