The flood events in 2002 and the heat wave of August 2003 in Europe had given evidence in a rather drastic way of our vulnerability and our non preparedness. The project has produced very important results that show that the concurrent work of different disciplines in addressing public health issues can produce innovative and useful results, providing an approach that can be followed on other public health issues. The project has shown that information on potential threats can be extremely useful in preparing the public for adverse events as well as facilitating the response when the events occur. This is a new dimension for public health which reverses the traditional thinking: from identifying and reducing specific risk factors, to taking action on the basis of prediction and early warning to prevent health consequences in large populations.