Provides in-depth, up-to-date explanations of essential pharmacology principles, including pharmacokinetics and pharmacodynamics, signal transduction mechanisms, pharmacogenetics, pharmacogenomics, and pharmacoeconomics; discusses the molecular, cellular, and integrated physiology of all organ systems, including the basis of motor function; covers mechanisms of action, clinical pharmacology, adverse effects, and practical aspects of drug use for the full range of anesthetic agents, as well as other durgs encountered in working with patients, including neuroprotective agents.