The new edition of this book is divided into two sections. The first covers basic concepts in treatment planning, including essential physics, and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, and high and low dose rate brachytherapy. The second part documents the practical clinical applications of these concepts in the treatment of different cancers. All of the chapters have been written by leaders in this field. This book should provide an invaluable guide to the basic technological factors and approaches in radiation therapy.